Carolon Multi-Layer Compression System


Carolon Multi-Layer compression provides a high quality compression system now containing a unique Cupron® Copper Yarn technology in the understockings, a fabric designed to reduce bacteria and fungi. Copper oxide remains effective for the life of the garment and is unaffected by washing and drying.


The VenUS IV trial was a “pragmatic randomised controlled trial; comparing the clinical and cost-effectiveness of two layer hosiery with four layer bandages, in terms of time to healing of venous leg ulcers”.[1]


34 centres participated across England and Northern Ireland, (n=457) from both community and primary care settings were recruited. The randomisation resulted in 230 participants allocated 2 layer hosiery as their therapy regime; of which 90 moved to non-trial treatment and 227 participants to standard care of 4 layer bandages; of which 70 moved to non-trial treatment.


The average time to heal was 99 days for the hosiery group compared to 98 days for the 4 layer bandage group. Recurrence within 1 year was 14.4% for the hosiery group vs. 23.3% for the 4 layer bandage group. The cost in the hosiery group was on average £302.4 less per participant per year, and on average the hosiery group had, 0.034 more QALYS per participant per year than the 4 layer bandage group.

Carolon clinical studies

New studies published

Author(s) Title Publication
Munro, G. Promoting patient centered choice of hosiery to aid compliance Wounds UK, 2013, Poster View


Author(s) Title Publication
Dumville, J. VenUS IV (Venous leg ulcer Study IV): A randomised controlled trial of compression hosiery versus compression bandaging in the treatment of venous leg ulcers. EWMA, 2013
Munro, G. Promoting patient centered choice of hosiery to aid compliance Wounds UK, 2013, Poster View