Replicine™ Functional Keratin® proteins have been shown to activate keratinocyte cells present in the wound and to stimulate them to quickly enter a hyperproliferative phase, an essential phase of wound healing[1].
Using Replicine Functional Technology, keragel and keragelT™ are keratin rich gels designed for full and partial thickness wounds, skin disorders and Epidermolysis Bullosa (EB). They help create a moist wound environment which promotes autolytic debridement and supports the wound healing process.
keragelT™ has a lower viscosity and so is thinner than keragel™, this is better suited to application to the delicate skin of EB patients.
keragel and keragelT have been evaluated on a variety of wounds including Epidermolysis Bullosa, donor sites, leg ulcers and chronic wounds in general. The results have consistently demonstrated the following benefits:
- Accelerates epithelialisation
- Faster healing
- Improves skin robustness
- Improves quality of life
- Reduces total cost of care
Keragel™ clinical studies
| Author(s) | Title | Publication | |
|---|---|---|---|
| Batzer, A.T., Marsh, C., Kirsner, R.S. | The use of keratin-based wound products on refractory wounds | Int Wound J. Feb 28. doi: 10.1111/iwj.12245 | View |
| Davidson, A., Jina, N.H., Marsh, C., Than, M., Simcock, J.W. | Do Functional Keratin Dressings Accelerate Epithelialization in Human Partial Thickness Wounds? A Randomized Controlled Trial on Skin Graft Donor Sites | ePlasty13e45 Aug 2013 | View |
| Kirsner, R.S., Cassidy, S., Marsh, C., Vivas, A., Kelly, R.J. | Use of a keratin-based wound dressing in the management of wounds in a patient with recessive dystrophic epidermolysis bullosa | Adv Skin and Wound Care. 2012, Sep;25(9): 400-3 | View |
| Pechter, P.M., Gil, J., Valdes, J., Tomic-Canic, M., Pastar, I., Stojadinovic, O., Kirsner R.S., Davis, S.C. | Keratin dressings speed epithelialization of deep partial-thickness wounds | Wound Repair and Regeneration. 2012, Mar-Apr; 20(2): 236-242 | View |
| Than, M.P., Smith R.A., Hammond, C., Kelly, R., Marsh, C., Maderal, A.D., Kirsner, R.S. | Keratin-based Wound Care Products for Treatment of Resistant Vascular Wounds | J Clin Aesthet Dermatol. 2012, Dec; 5(12): 31-5 | View |
| Than, M.P., Smith, R.A., Cassidy, S., Kelly, R., Marsh, C., Maderal, A., Kirsner, R.S. | Use of a keratin-based hydrogel in the management of recessive dystrophic epidermolysis bullosa | Journal of Dermatological Treatment. 2013, Aug; 24(4): 290-1 | View |
- P M Pechter, et al, Keratin dressings speed epithelialization of deep partial-thickness wounds. Wound Repair and Regeneration, (2012) vol 20, pp 236-242
